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Why does the shedding coincide with the dose increase

Gastroenterology 2024;166:S-591

This is a significant jump, quadrupling your original starting dose, and the effects typically match that increase

In post-processing, bursts were defined as 5 or more spikes with 100 ms separating each spike

These neurobiological alterations support depression, anxiety and other psychiatric disorders which, in turn, by chronicizing stress and structuring proinflammatory lifestyles (see below), reinforce and deepen them